In addition to a monthly seminar, optional secondments at partner sites, and the pairing with a consortium member as a mentor for the duration of the project, each QSPainRelief early-career scientists (ECS) will maintain a personal training portfolio that specifies individual training needs and goals, suggestions for Masterclass topics, and the desired mentor. During the annual general assembly (GA) meetings, QSPainRelief will organise ECS talks and/or poster sessions, and video-taped masterclasses that will be cut, animated, and subtitled within the following 6 months for publication on YouTube and on this page.
Training Documents
All ECS are asked to fill out and maintain this training portfolio in order to identify individual training needs and to monitor their progress. Please send the completed training portfolio to Dr. Nina Donner.
Project Video
QSPainRelief’s first patient event took place as part of Pain Alliance Europe’s (PAE) annual General Assembly (GA) Meeting on 24 June 2020. QSPainRelief’s scientific coordinator, Prof. Dr. Liesbeth de Lange, presented the scope of our Horizon 2020-funded research project in a 20-minute ppt presentation. The talk was well-received by the audience of laymen and European pain patient representatives from 19 different countries. Here, we share our introductory project video with students, the general public, and the patient community.
Masterclasses & Webinars
- QSPainRelief Masterclass 1 (PDF) – Approaches on the treatment of chronic pain in the clinic (Prof. Dr. Albert Dahan, December 2020)
This is the 1st QSPainRelief Masterclass, held by our scientific and ethical advisory board (SEAB) member Prof. Dr. Albert Dahan from Leiden University Medical Center (LUMC) in Leiden, The Netherlands, during the project’s 2nd General Assembly (GA) Meeting on December 10th, 2020. As an expert on chronic pain treatment, he provides detailed insight into the current approaches used in the clinical treatment of chronic pain patients.
- QSPainRelief Masterclass 2 (PDF) – Operant self-administration animal models: Evaluating reward, reinforcement, abuse liability, and addiction (Prof. Dr. Rafael Maldonado, December 2020)
This is the 2nd QSPainRelief Masterclass, held by the leader of work package 6 (WP6), Prof. Dr. Rafael Maldonado from University Pompeu Fabra (UPF, Barcelona, Spain), during the project’s 2nd General Assembly (GA) Meeting on December 10th, 2020. As an expert on preclinical research regarding nociception (pain perception), pain medication, and the development of addiction, Rafael elucidates the value and necessity of animal models in researching addictive behaviors and related brain regions. In particular, we learn everything about operant self-administration of opioids (or any other potential “drug”, including alcohol or food) in animal models of reward, reinforcement, abuse liability, and addiction.
- QSPainRelief Masterclass 3 (PDF) – Molecular modeling and dynamic simulations of G protein-coupled receptors (GPCRs) (Prof. Dr. Jesús Giraldo, December 2021)
This is the 3rd QSPainRelief Masterclass, held by the leader of work package 5 (WP5), Prof. Dr. Jesús Giraldo from Universitat Autònoma de Barcelona (UAB, Barcelona, Spain), during the project’s 3rd General Assembly (GA) Meeting on December 15th, 2021. Jesús Giraldo leads the Laboratory of Molecular Neuropharmacology and Bioinformatics at the Institut de Neurociències. The research activities of the group that are related to the present project are mostly devoted to the elucidation of the signalling properties of G-protein-coupled receptors (GPCRs) by computational methods.
- QSPainRelief Masterclass 4 (PDF) – CNS quantitative systems biology in the research of new drugs (Robert Carr and Dr. Athan Spiros, December 2021)
This is the 4th QSPainRelief Masterclass, held by project members from In Silico Biosciences Inc. (ISB), namely Robert Carr (CEO) and Athan Spiros, Ph.D. ISB is a biosciences company located in Lexington, USA, that specializes in computer-based mechanistic modeling of central nervous system (CNS) diseases. The Masterclass was held online due to the pandemic and recorded via Zoom on December 15th, 2021, within the realm of the remote 3rd QSPainRelief General Assembly (GA) Meeting.
- QSPainRelief Masterclass 5 (PDF) – The miracle of smart data in unravelling pharmacokinetic- and pharmacodynamic relationships (Prof. Dr. Liesbeth de Lange, December 2022)
This is the 5th QSPainRelief Masterclass, held by the project’s scientific coordinator, Prof. Dr. Liesbeth de Lange from Leiden University (ULEI), within the realm of the 4th General Assembly (GA) Meeting in Barcelona, Spain, on 5 December 2022. We hope you enjoy Liesbeth’s comprehensive storytelling about the decades-long achievements of her research group and the role smart data and mathematical modelling play in unravelling pharmacokinetic and pharmacodynamic relationships.
- QSPainRelief Masterclass 6 (PDF) – Human biomarkers of nociception: Potential tools for the prevention, diagnosis and personalised treatment of chronic pain? (Prof. Dr. André Mouraux, December 2022)
This fascinating 6th QSPainRelief Masterclass about “Human biomarkers of nociception” was held by work package 8 (WP8) leader Prof. Dr. André Mouraux from UCLouvain (UCL), Belgium, within the realm of the 4th General Assembly (GA) Meeting in Barcelona, Spain, on 5 December 2022. Sit back, relax, and enjoy André’s comprehensive overview of the ongoing research in pain perception (nociception) and outlook to the future when we might have tools and methods to prevent, diagnose, and treat chronic pain with a personalised approach.
- QSPainRelief Masterclass 7 (PDF) – Patient Partnerships in Research: How we can co-create the future of research from bench to bedside? (Deirdre Ryan, December 2023)
In this insightful 7th QSPainRelief Masterclass, Deirdre Ryan, President of Pain Alliance Europe (PAE), discusses the importance of patient involvement in healthcare research, highlighting challenges and strategies for meaningful engagement. She emphasises the need for better patient-reported outcome measures and the mutual benefits of collaboration between patients and researchers.
- QSPainRelief Masterclass 8 (PDF) – Exploring the multidimensional complexity of opioid receptors to develop improved therapeutics: From innovative peptides to Quantitative Systems Pharmacology platforms
(Prof. Dr. Andrea Bedini, December 2025)
In our 8th and last Masterclass, Prof. Dr. Andrea Bedini (UNIBO) dove into the depths of molecular biology and intracellular signalling mechanisms, providing a comprehensive overview about the complexity and therapeutic potential of an essential group of G-protein-coupled receptors (GPCR), namely opioid receptors. How can we exploit them better to improve therapeutic treatments for chronic pain patients? The keynote lecture was held on 10th December 2024 as part of the Final QSPainRelief GA Meeting in Bologna, Italy.